Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/79534
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Type: Journal article
Title: PH-responsive nutraceutical-mesoporous silica nanoconjugates with enhanced colloidal stability
Author: Guillet-Nicolas, R.
Popat, A.
Bridot, J.
Monteith, G.
Qiao, S.
Kleitz, F.
Citation: Angewandte Chemie International Edition, 2013; 52(8):2318-2322
Publisher: Wiley-V C H Verlag GMBH
Issue Date: 2013
ISSN: 1433-7851
1521-3773
Statement of
Responsibility: 
Rémy Guillet-Nicolas, Amirali Popat, Jean-Luc Bridot, Gregory Monteith, Shi Zhang Qiao, and Freddy Kleitz
Abstract: An innovative platform for targeted oral drug delivery is proposed based on the functionalization of drug/dye-loaded mesoporous silica nanoparticles (MSNs) with a biodegradable nutraceutical (β-lactoglobulin). The attachment of the nutraceutical not only protects the drug/dye from leaching in acidic environment, but also effectively allows their release in desired basic sites (pH 7.4).
Keywords: β-lactoglobulin
colloidal stability
mesoporous silica
nutraceutical
oral drug delivery
Rights: Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
DOI: 10.1002/anie.201208840
Appears in Collections:Aurora harvest 4
Chemical Engineering publications

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