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Type: Journal article
Title: Transgenerational, dynamic methylation of stomata genes in response to low relative humidity
Author: Tricker, P.
Rodriguez Lopez, C.
Gibbings, J.
Hadley, P.
Wilkinson, M.
Citation: International Journal of Molecular Sciences, 2013; 14(4):6674-6689
Publisher: MDPI AG
Issue Date: 2013
ISSN: 1661-6596
Statement of
Penny J. Tricker, Carlos M. Rodríguez López, George Gibbings, Paul Hadley and Mike J. Wilkinson
Abstract: Transgenerational inheritance of abiotic stress-induced epigenetic modifications in plants has potential adaptive significance and might condition the offspring to improve the response to the same stress, but this is at least partly dependent on the potency, penetrance and persistence of the transmitted epigenetic marks. We examined transgenerational inheritance of low Relative Humidity-induced DNA methylation for two gene loci in the stomatal developmental pathway in Arabidopsis thaliana and the abundance of associated short-interfering RNAs (siRNAs). Heritability of low humidity-induced methylation was more predictable and penetrative at one locus (SPEECHLESS, entropy ≤ 0.02; χ2 < 0.001) than the other (FAMA, entropy ≤ 0.17; χ2 ns). Methylation at SPEECHLESS correlated positively with the continued presence of local siRNAs (r2 = 0.87; p = 0.013) which, however, could be disrupted globally in the progeny under repeated stress. Transgenerational methylation and a parental low humidity-induced stomatal phenotype were heritable, but this was reversed in the progeny under repeated treatment in a previously unsuspected manner.
Rights: © 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (
RMID: 0020126585
DOI: 10.3390/ijms14046674
Appears in Collections:Agriculture, Food and Wine publications

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