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Type: Journal article
Title: Intraorbital corticosteroid injection for orbital reactive lymphoid hyperplasia
Author: Andrew, N.
Kearney, D.
Selva-Nayagam, D.
Citation: Eye, 2013; 27(4):561-563
Publisher: Nature Publishing Group
Issue Date: 2013
ISSN: 0950-222X
Statement of
NH Andrew, D Kearney and D Selva
Abstract: PURPOSE The purpose of this study is to assess the utility of intraorbital injection of triamcinolone acetonide as a primary treatment option for orbital reactive lymphoid hyperplasia (RLH). PATIENTS AND METHOD Retrospective, single-centre, interventional case series. RESULTS Intraorbital injection of triamcinolone acetonide was associated with complete resolution of all symptoms and signs in four cases (80%). This was achieved with a single injection in two cases and with two injections in another two cases. Radiological resolution was confirmed in one case. One case developed bilateral multifocal orbital RLH lesions 1 month after the second injection. CONCLUSION Intraorbital injection of corticosteroid may be a useful treatment option for orbital RLH, and may have a role as a first-line therapy in RLH of the anterior orbit. A significant proportion of patients may require repeat injections to achieve resolution. A larger prospective study is required to validate our findings.
Keywords: reactive lymphoid hyperplasia
lymphoproliferative disorders
drug therapy
orbital disease
Rights: © 2013 Macmillan Publishers Limited All rights reserved
DOI: 10.1038/eye.2012.288
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Appears in Collections:Aurora harvest 4
Opthalmology & Visual Sciences publications

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