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Type: Journal article
Title: Muscle-specific kinase antibody positive myaesthenia gravis and multiple sclerosis co-presentation: A case report and literature review
Author: Sylvester, J.
Purdie, G.
Slee, M.
Gray, J.
Burnet, S.
Koblar, S.
Citation: Journal of Neuroimmunology, 2013; 264(1-2):130-133
Publisher: Elsevier Science BV
Issue Date: 2013
ISSN: 0165-5728
Statement of
Jessica Sylvester, Grant Purdie, Mark Slee, James X. Gray, Simon Burnet, Simon Koblar
Abstract: We present the first case of simultaneous muscle-specific kinase antibody positive myaesthenia gravis and relapsing-remitting multiple sclerosis to be reported in the English literature along with the inherent diagnostic and treatment challenges. There may be an association between myaesthenia and central nervous system demyelination. We identified 72 previously published cases of myaesthenia with central nervous system demyelination. Of 19 cases of myaesthenia with relapsing-remitting multiple sclerosis, nine (47%) were acetylcholine receptor antibody negative, but there were no previously published cases with muscle-specific kinase antibody. Further research is required to clarify this association and optimal treatment in such cases.
Keywords: Myaesthenia gravis
Multiple sclerosis
Muscle-specific kinase antibody
Rights: Copyright © 2013 Elsevier B.V. Published by Elsevier B.V. All rights reserved.
DOI: 10.1016/j.jneuroim.2013.08.016
Appears in Collections:Aurora harvest
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