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Type: Journal article
Title: Pioneering contributions by Robert Edwards to oocyte in vitro maturation (IVM)
Author: Thompson, J.
Gilchrist, R.
Citation: Molecular Human Reproduction, 2013; 19(12):794-798
Publisher: Oxford Univ Press
Issue Date: 2013
ISSN: 1360-9947
Statement of
J.G. Thompson and R.B. Gilchrist
Abstract: The history of in vitro maturation (IVM) of mammalian oocytes, especially of human oocytes, holds a special place for Robert Edwards. He was the first to comprehensively examine and demonstrate maturation of human oocytes in vitro and in so doing he changed the course of medicine by fertilizing them in vitro. In reviewing his contribution, we have examined the state of the field at the time and discuss his pioneering insights into mammalian oocyte biology. We will also discuss how some of the major concepts and challenges identified by Edwards 50 years ago remain among the major challenges facing IVM today.
Keywords: oocyte maturation; embryology
Rights: © The Author 2013. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved
RMID: 0020133521
DOI: 10.1093/molehr/gat075
Appears in Collections:Obstetrics and Gynaecology publications

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