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Type: Journal article
Title: Generalized anxiety disorder prevalence and comorbidity with depression in coronary heart disease: a meta-analysis
Author: Tully, P.
Cosh, S.
Citation: Journal of Health Psychology, 2013; 18(12):1601-1616
Publisher: Sage Publications Ltd
Issue Date: 2013
ISSN: 1359-1053
Statement of
Phillip J Tully and Suzanne M Cosh
Abstract: Generalized anxiety disorder prevalence and comorbidity with depression in coronary heart disease patients remain unquantified. Systematic searching of Medline, Embase, SCOPUS and PsycINFO databases revealed 1025 unique citations. Aggregate generalized anxiety disorder prevalence (12 studies, N = 3485) was 10.94 per cent (95% confidence interval: 7.8-13.99) and 13.52 per cent (95% confidence interval: 8.39-18.66) employing Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria (random effects). Lifetime generalized anxiety disorder prevalence was 25.80 per cent (95% confidence interval: 20.84-30.77). In seven studies, modest correlation was evident between generalized anxiety disorder and depression, Fisher's Z = .30 (95% confidence interval: .19-.42), suggesting that each psychiatric disorder is best conceptualized as contributing unique variance to coronary heart disease prognosis.
Keywords: comorbidity; coronary heart disease; depression; generalized anxiety disorder; meta-analysis
Rights: © The Author(s) 2012
RMID: 0020133600
DOI: 10.1177/1359105312467390
Appears in Collections:Medicine publications

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