Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/82591
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Type: Journal article
Title: Evolution and biology of supernumerary B chromosomes
Author: Houben, A.
Banaei-Moghaddam, A.
Klemme, S.
Timmis, J.
Citation: Cellular and Molecular Life Sciences, 2014; 71(3):467-478
Publisher: Birkhauser Verlag Ag
Issue Date: 2014
ISSN: 1420-682X
1420-9071
Statement of
Responsibility: 
Andreas Houben, Ali Mohammad Banaei-Moghaddam, Sonja Klemme, Jeremy N. Timmis
Abstract: B chromosomes (Bs) are dispensable components of the genome exhibiting non-Mendelian inheritance and have been widely reported on over several thousand eukaryotes, but still remain an evolutionary mystery ever since their first discovery over a century ago [1]. Recent advances in genome analysis have significantly improved our knowledge on the origin and composition of Bs in the last few years. In contrast to the prevalent view that Bs do not harbor genes, recent analysis revealed that Bs of sequenced species are rich in gene-derived sequences. We summarize the latest findings on supernumerary chromosomes with a special focus on the origin, DNA composition, and the non-Mendelian accumulation mechanism of Bs.
Keywords: B chromosome
Genome evolution
Drive
Selfish chromosome
Next generation sequencing
Rights: © Springer Basel 2013
DOI: 10.1007/s00018-013-1437-7
Appears in Collections:Aurora harvest
Molecular and Biomedical Science publications

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