Please use this identifier to cite or link to this item:
Scopus Web of Science® Altmetric
Type: Journal article
Title: Fos-icking for control of angiogenesis: Increasing the longevity of peritoneal dialysis
Author: Bonder, C.
Ebert, L.
Citation: Kidney International, 2013; 84(6):1065-1067
Publisher: Blackwell Publishing Inc
Issue Date: 2013
ISSN: 0085-2538
Statement of
Claudine S. Bonder and Lisa M. Ebert
Abstract: Recurring peritonitis reduces the effectiveness of peritoneal dialysis by increasing fibrosis and angiogenesis, ultimately causing ultrafiltration failure (UFF). Identifying the processes underlying UFF will provide new hope for patients with chronic kidney disease. Catar and colleagues demonstrate that transforming growth factor-β, tumor necrosis factor-α, and interleukin-1 synergize to significantly increase the production and release of vascular endothelial growth factor by mesothelial cells, which, if untreated, will promote peritoneal angiogenesis, leading to UFF.
Keywords: Peritoneum
Epithelial Cells
Vascular Endothelial Growth Factor A
Proto-Oncogene Proteins c-fos
Transcription, Genetic
Rights: © 2013 International Society of Nephrology
DOI: 10.1038/ki.2013.306
Appears in Collections:Aurora harvest 4
Medicine publications

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.