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Type: Journal article
Title: The gut-brain axis in the critically ill: is glucagon-like peptide-1 protective in neurocritical care?
Author: Plummer, M.
Meier, J.
Deane, A.
Citation: Critical Care, 2013; 17(4):1-2
Publisher: Current Science Ltd
Issue Date: 2013
ISSN: 1466-609X
Statement of
Mark P Plummer, Juris J Meier and Adam M Deane
Abstract: Enteral nutrient is a potent glucagon-like peptide-1 (GLP-1) secretagogue. In vitro and animal studies indicate that GLP-1 has immune-modulatory and neuroprotective effects. To determine whether these immune-modulatory and neuroprotective effects of GLP-1 are beneficial in the critically ill, studies achieving pharmacological GLP-1 concentrations are warranted.
Keywords: Humans; Enteral Nutrition; Immunity, Cellular; Intensive Care Units; Female; Male; Glucagon-Like Peptide 1
Rights: Copyright status unknown
RMID: 0020136043
DOI: 10.1186/cc12758
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Appears in Collections:Anaesthesia and Intensive Care publications

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