Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/82869
Citations
Scopus Web of Science® Altmetric
?
?
Type: Journal article
Title: Biomimetic total synthesis of (±)-yezo'otogirin A
Other Titles: Biomimetic total synthesis of (+/-)-yezo'otogirin A
Author: Lam, H.
Kuan, K.
George, J.
Citation: Organic and Biomolecular Chemistry, 2014; 12(16):2519-2522
Publisher: Royal Society of Chemistry
Issue Date: 2014
ISSN: 1477-0520
1477-0539
Organisation: Institute for Photonics & Advanced Sensing (IPAS)
Statement of
Responsibility: 
Hiu C. Lam, Kevin K. W. Kuan and Jonathan H. George
Abstract: The total synthesis of yezo'otogirin A has been achieved via a biosynthetically-inspired strategy. Diastereoselective synthesis of pre-yezo'otogirin A, the proposed biosynthetic pre-cursor of yezo'otogirin A, was accomplished in eight steps from 3-ethoxy-2-cyclohexenone. A biomimetic oxidative radical cyclization was then used to construct the unique tricyclic ring system of yezo'otogirin A. The synthesis showcases the ability of biomimetic radical cyclizations to generate complex natural products from unprotected intermediates.
Keywords: Heterocyclic Compounds, 3-Ring
Molecular Conformation
Stereoisomerism
Biomimetic Materials
Rights: © Royal Society of Chemistry 2014
DOI: 10.1039/c4ob00186a
Grant ID: http://purl.org/au-research/grants/arc/DE130100689
Appears in Collections:Aurora harvest 4
IPAS publications

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.