Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/82914
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Type: Journal article
Title: Longitudinal weight gain in women identified with polycystic ovary syndrome: results of an observational study in young women
Author: Teede, H.
Joham, A.
Paul, E.
Moran, L.
Loxton, D.
Jolley, D.
Lombard, C.
Citation: Obesity, 2013; 21(8):1526-1532
Publisher: North Amer Assoc Study Obesity
Issue Date: 2013
ISSN: 1930-7381
1930-739X
Statement of
Responsibility: 
Helena J. Teede, Anju E. Joham, Eldho Paul Lisa J. Moran, Deborah Loxton, Damien Jolley and Catherine Lombard
Abstract: Objective: Polycystic ovary syndrome (PCOS) affects 6-18% of women. The natural history of weight gain in women with PCOS has not been well described. Here we aimed to examine longitudinal weight gain in women with and without PCOS and to assess the association between obesity and PCOS prevalence. Design and Methods: The observational study was set in the general community. Participants were women randomly selected from the national health insurance scheme (Medicare) database. Mailed survey data were collected by the Australian Longitudinal Study on Women's Health. Data from respondents to survey 4, aged 28-33 years (2006, n = 9,145) were analyzed. The main outcome measures were PCOS prevalence and body mass index (BMI). Results: Self-reported PCOS prevalence was 5.8% (95% CI: 5.3%-6.4%). Women reporting PCOS had higher weight, mean BMI [2.5 kg/m2 (95% CI: 1.9-3.1)], and greater 10-year weight gain [2.6 kg (95% CI: 1.2-4.0)]. BMI was the strongest correlate of PCOS status with every BMI increment increasing the risk of reporting PCOS by 9.2% (95% CI: 6%-12%). Conclusions: This community based observational study with longitudinal reporting of weight shows that weight, BMI, and 10-year weight gain were higher in PCOS. We report the novel finding that obesity and greater weight gain are significantly associated with PCOS status. Considering the prevalence, major health and economic burden of PCOS, the increasing weight gain in young women, and established benefits of weight loss, these results have major public health implications.
Keywords: Humans
Polycystic Ovary Syndrome
Obesity
Weight Gain
Weight Loss
Body Mass Index
Health Surveys
Prevalence
Multivariate Analysis
Logistic Models
Longitudinal Studies
Adult
Women's Health
Australia
Female
Self Report
Rights: © 2012 The Obesity Society
DOI: 10.1002/oby.20213
Published version: http://dx.doi.org/10.1002/oby.20213
Appears in Collections:Aurora harvest 4
Obstetrics and Gynaecology publications

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