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Type: Journal article
Title: Takotsubo cardiomyopathy after anti-influenza vaccination: catecholaminergic effects of immune system
Author: Singh, K.
Marinelli, T.
Horowitz, J.
Citation: American Journal of Emergency Medicine, 2013; 31(11):1627.e1-1627.e4
Publisher: W B Saunders Co
Issue Date: 2013
ISSN: 0735-6757
Statement of
Kuljit Singh, Tina Marinelli, John D Horowitz
Abstract: Takotsubo cardiomyopathy (TTC) is a well-known condition, which leads to sudden transient regional systolic dysfunction. It mostly affects aging women and is usually precipitated by emotional or physical stress. Despite the tremendous amount of literature on TTC, cardiac sympathetic hyperactivity is the only thing known to be associated with pathogenesis. In our case, an elderly woman presented with an acute episode of TTC 24 hours after anti-influenza vaccination without any obvious stressor for sudden rise in the catecholamine level. Sudden postvaccination change in the cardiac sympathetic discharge is the most likely precipitant of TTC in this case.
Keywords: Humans; Normetanephrine; Metanephrine; Influenza Vaccines; Echocardiography; Aged, 80 and over; Female; Takotsubo Cardiomyopathy
Rights: © 2013 Elsevier Inc. All rights reserved.
RMID: 0020137235
DOI: 10.1016/j.ajem.2013.06.039
Appears in Collections:Medicine publications

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