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|Title:||Evaluating long-term attachment of two different endoclips in the human gastrointestinal tract|
|Citation:||Gastrointestinal Endoscopy, 2010; 16(2):344-348|
|Hendrik Albert Maurits Swellengrebel, Cornelia Adriana Maria Marijnen, Andrew Vincent, Annemieke Cats|
|Abstract:||<h4>Aim</h4>To evaluate the long-term attachment of two types of endoclips in the human gastrointestinal tract.<h4>Methods</h4>In this prospective observational study, endoclips were placed and followed-up during endoscopies or using fluoroscopic images as part of a prospective feasibility study evaluating external beam radiotherapy (EBRT, wk 1-3) followed by high dose rate brachytherapy (HDRBT with an endoluminal applicator once a week for 3 wk, wk 9-11) in medically inoperable rectal cancer patients. Initially, the type and number of endoclips were chosen randomly and later refined to 1 Resolution(®) clip (Microvasive) proximal and 2 Quickclips(®) (Olympus) distal to the tumor. Nine consecutive patients, included between September 2007 and August 2008 were analyzed. Retention rates were evaluated over three different observational periods [period 1: pre-HDRBT (wk -2-8), period 2: during HDRBT (wk 9-11) and period 3: post-HDRBT (wk 12-16)].<h4>Results</h4>In this study, a total of 44 clips were placed during endoscopy, either at the beginning or at the end of period 1. The Resolution clip had a higher overall retention rate than the Quickclip (P = 0.01). After a median period of 81 d after placement (in period 1), long-term retention rates for the Resolution clip and Quickclip clip were 67% and 35% respectively.<h4>Conclusion</h4>The Resolution clip has a high retention rate and is useful in situations where long-term attachment to the human gastrointestinal mucosa is warranted.|
|Keywords:||Endoclip; Radiotherapy; Retention rate; Cancer; Delineation|
|Rights:||©2010 Baishideng Publishing Group Co., Limited. All rights reserved.|
|Appears in Collections:||Medicine publications|
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