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Type: Journal article
Title: Obstructive sleep apnoea: from pathogenesis to treatment: current controversies and future directions
Author: Eastwood, P.
Malhotra, A.
Palmer, L.
Kezirian, E.
Horner, R.
Ip, M.
Thurnheer, R.
Antic, N.
Hillman, D.
Citation: Respirology, 2010; 15(4):587-595
Publisher: Blackwell Publishing Asia
Issue Date: 2010
ISSN: 1323-7799
Statement of
Peter R. Eastwood, Atul Malhotra, Lyle J. Palmer, Eric J. Kezirian, Richard L. Horner, Mary S. Ip, Robert Thurnheer, Nick A. Antic and David R. Hillman
Abstract: Obstructive sleep apnoea (OSA) is a common disease, recognized as an independent risk factor for a range of clinical conditions, such as hypertension, stroke, depression and diabetes. Despite extensive research over the past two decades, the mechanistic links between OSA and other associated clinical conditions, including metabolic disorders and cardiovascular disease, remain unclear. Indeed, the pathogenesis of OSA itself remains incompletely understood. This review provides opinions from a number of leading experts on issues related to OSA and its pathogenesis, interaction with anaesthesia, metabolic consequences and comorbidities, cardiovascular disease, genetics, measurement and diagnosis, surgical treatment and pharmacotherapeutic targets.
Keywords: pathogenesis; treatment; sleep apnoea syndrome
Rights: © 2010 The Authors
RMID: 0020136638
DOI: 10.1111/j.1440-1843.2009.01699.x
Appears in Collections:Medicine publications

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