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Type: Journal article
Title: Effectiveness of two mouth rinses solutions in arresting caries lesions: a short-term clinical trial
Author: Guimaraes, A.
De Anselmo Peres, M.
Vieira, R.
Ramos-Jorge, M.
Modesto, A.
Citation: Oral Health and Preventive Dentistry, 2008; 6(3):231-238
Publisher: Quintessence Publishing Co Ltd
Issue Date: 2008
ISSN: 1602-1622
Statement of
Ana Rita Duarte, Marco Aurélio Peres, Ricardo Sousa Vieira, Maria Letícia Ramos-Jorge, Adriana Modesto
Abstract: <h4>Purpose</h4>To clinically evaluate the additional effect of adding 0.12% chlorhexidine digluconate (CHX) to a 0.05% sodium fluoride (NaF) mouth rinse in arresting active enamel caries lesions after 28 days.<h4>Materials and methods</h4>A short-term double-blind clinical trial that included a total of 170 children, aged 11 to 15 years, with active smooth surface caries lesions (average 6.52) was conducted. The participants were enrolled and randomly distributed into two equal groups. Under the supervision of the research team, the children rinsed with a 15 ml solution of either 0.05% NaF (G1) or 0.05% NaF + 0.12% CHX (G2) for 1 min/day for 28 days. A clinical examination was carried out at the beginning and at the end of the study with children who underwent supervised tooth brushing. A calibrated examiner, who was unaware of the treatment given to each subject, examined all smooth surfaces dried with compressed air, isolated and illuminated with a reflector. The surface was considered active (A) or arrested (I). The frequency of A or I surfaces was evaluated by calculating the difference between the number found at the beginning and at the end of the trial.<h4>Results</h4>No significant differences were detected between the two groups with respect to caries lesion surfaces at baseline (6.49 +/- 4.45 - G1, 6.55 +/- 4.23 - G2, respectively), nor were differences found when age and gender wer taken into consideration. Arrestment proportions were 84.4% (G1) and 85.3% (G2) (P = 0.71; not significant).<h4>Conclusions</h4>Although both solutions showed high arrestment proportions, the addition of CHX did not improve the arrestment capacity of the NaF mouth rinse.
Keywords: chlorhexidine
dental caries
randomised controlled trial
Rights: Copyright of Oral Health & Preventive Dentistry is the property of Quintessence Publishing Company Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder’s express written permission. However, users may print, download, or email articles for individual use.
DOI: 10.3290/j.ohpd.a13970
Appears in Collections:Aurora harvest
Dentistry publications

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