Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/84511
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Type: Journal article
Title: Carbon nanotubes as an advanced drug and gene delivery nanosystem
Author: Dolatabadi, J.
Omidi, Y.
Losic, D.
Citation: Current Nanoscience, 2011; 7(3):297-314
Publisher: Bentham Science Publishers
Issue Date: 2011
ISSN: 1573-4137
1875-6786
Statement of
Responsibility: 
Jafar Ezzati Nazhad Dolatabadi, Yadollah Omidi and Dusan Losic
Abstract: New nanomaterials have been extensively explored in recent years for drug delivery applications to address problems associated with the conventional drug therapies such as limited drug solubility, poor biodistribution, lack of selectivity and unfavourable pharmacokinetics. Among them, carbon nanotubes (CNTs) have attracted great attention due to their unique physicochemical architecture and properties. This comprehensive review summarizes the recent advances regarding the use of CNTs for drug delivery. This review includes general information about CNT structures and properties, methods for their dispersion in aqueous solution and basic concepts for CNTs functionalization relevant for their applications in biological systems and delivery of therapeutics. Some toxicological and biocompatibility issues related to the use of CNTs as pharmaceutical excipients are discussed. Last, recent progress on development of CNT drug delivery systems with a specific emphasis on gene delivery was reviewed.
Rights: Copyright status unknown
RMID: 0020127859
DOI: 10.2174/157341311795542444
Appears in Collections:Chemical Engineering publications

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