Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/8461
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Type: Journal article
Title: The willingness of women to participate in a long-term trial of hormone replacement therapy: a qualitative study using focus groups
Author: Hepworth, J.
Paine, B.
Miles, H.
Marley, J.
MacLennan, A.
Citation: Psychology, Health & Medicine, 2002; 7(4):469-476
Publisher: Carfax Publishing Limited
Issue Date: 2002
ISSN: 1354-8506
1465-3966
Statement of
Responsibility: 
J. Hepworth; B. Paine; H. Miles; J. Marley; A. MacLennan
Abstract: The actual proportion of eligible people who participate in clinical trials is low. Consequently, a qualitative study of the willingness of women who are postmenopausal to participate in a long-term randomized control trial of hormone replacement therapy (HRT) designed to investigate the prevention of degenerative diseases was conducted. Focus group methodology was employed to explore the personal and social aspects of decision making about trial participation. Participants were randomly selected from the patient age-sex registers of four University of Adelaide general practices. Twenty-one women participated in four focus groups. The reasons for and against trial participation were examined using qualitative content analysis; ( n = 18) women were unwilling to participate in the trial. The lack of perceived individual benefit, minimal altruism, the risk of breast cancer and side effects, not wanting to take unnecessary medication, a ten-year commitment, and negative experiences of HRT use, were the main reasons given for not entering the trial. Of the few women ( n = 3) who clearly would enter the trial, free prescriptions and a positive history of using HRT were the main reasons for participation. The perceived disadvantages of clinical trials of HRT deter women from participating in a long-term clinical trial of HRT. An investment in education and information to eligible participants about both the risks and potential benefits of HRT may improve trial recruitment.
Keywords: Allied Health; Behavioral Medicine; Health & Illness; Health Counseling; Health Psychology; Medical Sociology
Description: © 2008 Informa plc
RMID: 0020021322
DOI: 10.1080/1354850021000015285
Appears in Collections:Obstetrics and Gynaecology publications

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