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Type: Journal article
Title: Risk factors for the deterioration of glucose metabolism in polycystic ovary syndrome
Author: Wang, J.
Norman, R.
Citation: Reproductive Biomedicine Online, 2004; 9(2):201-204
Publisher: Reproductive Healthcare Ltd.
Issue Date: 2004
ISSN: 1472-6483
Statement of
Jim Wang and Robert J. Norman
Abstract: Women with polycystic ovary syndrome (PCOS) have a high risk of abnormal glucose metabolism, which deteriorates gradually over time. This study was designed to assess contributing factors to the rate of deterioration of glucose metabolism over the 4- to 7-year follow-up period. The study group included 67 PCOS women who had normal glucose tolerance in the initial test in 1990-1992. There was a significant increase in both fasting and 2-h glucose concentrations, and body weight, over the follow-up period. The initial obesity, expressed as waist:hip ratio and BMI, was significantly related to the increase of glucose concentrations, while weight gain was not a significant factor. The overweight/obese PCOS women have a faster deterioration of glucose metabolism over the follow-up period than the non-obese ones. Moderate weight gain has no significant detrimental effect on the rate of deterioration of glucose metabolism.
Keywords: Diabetes
glucose metabolism
Description: © Reproductive Biomedicine Online
DOI: 10.1016/S1472-6483(10)62130-X
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Appears in Collections:Aurora harvest 4
Obstetrics and Gynaecology publications

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