Adelaide Research & Scholarship
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https://hdl.handle.net/2440/86036
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| Type: | Journal article |
| Title: | Apparent non-involvement of prions in the pathogenesis of spongiform change in HIV-infected brain |
| Author: | Goldwater, P.N. Paton, J.C. |
| Citation: | Journal of Neuropathology and Experimental Neurology, 1989; 48(2):184-186 |
| Publisher: | Lippincott, Williams & Wilkins |
| Issue Date: | 1989 |
| ISSN: | 0022-3069 1554-6578 |
| Statement of Responsibility: | Paul N. Goldwater and James C. Paton |
| Abstract: | Characteristic neuropathological white matter changes in the brains of patients dying from the acquired immune deficiency syndrome (AIDS) suggest pathogenetic involvement of either the PrP₂₇₋₃₀ gene or a scrapie-related prion; however, proteinase-K resistant scrapie-like proteins could not be detected in brain tissue from AIDS patients. |
| Keywords: | AIDS (aquired immune deficiency syndrome) encephalopathy Human immunodeficiency virus (HIV) Pathogenetic mechanisms Scrapie prion |
| Rights: | © 1989 American Association of Neuropathologists, Inc |
| DOI: | 10.1097/00005072-198903000-00005 |
| Published version: | http://dx.doi.org/10.1097/00005072-198903000-00005 |
| Appears in Collections: | Aurora harvest 2 Molecular and Biomedical Science publications |
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