Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/8608
Citations
Scopus Web of ScienceĀ® Altmetric
?
?
Type: Journal article
Title: Nutrition, oseoporosis and aging
Author: Nordin, B.
Need, A.
Steurer, T.
Morris, H.
Chatterton, B.
Horowitz, M.
Citation: Annals of the New York Academy of Sciences, 1998; 854(1 TOWARDS PROLO):336-351
Publisher: NEW YORK ACAD SCIENCES
Issue Date: 1998
ISSN: 0077-8923
1749-6632
Statement of
Responsibility: 
B. E. Christopher Nordin, Allan G. Need, Tracy Steurer, Howard A. Morris, Barry E. Chatterton And Michael Horowitz
Abstract: Loss of bone is an almost universal accompaniment of aging that proceeds at an average rate of 0.5-1% per annum from midlife onwards. There are at least four nutrients involved in this process: calcium, salt, protein, and vitamin D, at least in women. The pathogenesis of osteoporosis in men is more obscure. Calcium is a positive risk factor because calcium requirement rises at the menopause due to an increase in obligatory calcium loss and a small reduction in calcium absorption that persist to the end of life. A metaanalysis of 20 calcium trials shows that this process can generally be arrested by calcium supplementation, although there is some doubt about its effectiveness in the first few years after menopause. Salt is a negative risk factor because it increases obligatory calcium loss; every 100 mmol of sodium takes 1 mmol of calcium out of the body. Restricting salt intake lowers the rate of bone resorption in postmenopausal women. Protein is another negative risk factor; increasing animal protein intake from 40 to 80 g daily increases urine calcium by about 1 mmol/day. Low protein intakes in third world countries may partially protect against osteoporosis. Vitamin D (sometimes called a nutrient and sometimes a hormone) is important because age-related vitamin D deficiency leads to malabsorption of calcium, accelerated bone loss, and increased risk of hip fracture. Vitamin D supplementation has been shown to retard bone loss and reduce hip fracture incidence in elderly women.
Keywords: Animals; Humans; Osteoporosis; Vitamin D; Diet; Aging; Sex Characteristics; Aged; Middle Aged; Female; Male; Nutritional Physiological Phenomena
RMID: 0030005114
DOI: 10.1111/j.1749-6632.1998.tb09914.x
Appears in Collections:Medicine publications

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.