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dc.contributor.authorBakker, J.-
dc.contributor.authorDe Vos, R.-
dc.contributor.authorPel, M.-
dc.contributor.authorWisman, C.-
dc.contributor.authorvan Lith, J.-
dc.contributor.authorMol, B.-
dc.contributor.authorvan der Post, J.-
dc.identifier.citationBJOG: an International Journal of Obstetrics and Gynaecology, 2009; 116(4):562-568-
dc.descriptionArticle first published online: 18 FEB 2009-
dc.description.abstractObjective:  The objective of this study was to compare outcomes of induced labour with intravenous oxytocin with a start in the evening versus in the morning. Design:  Randomised controlled trial. Setting:  Labour wards of three hospitals in Amsterdam, the Netherlands. Participants:  Women with an indication for induction of labour with intravenous oxytocin. Methods:  Included women were randomized to either the evening group with a start of induction of labour at 21:00 hours, or the morning group with a start at 07:00 hours. Main outcome measures:  Primary outcome was duration of labour. Secondary outcomes were instrumental delivery rate, adverse neonatal outcome defined as an Apgar score below 7 after 5 minutes, number and indications of paediatric consults and neonatal admissions, duration of second stage, number of intrapartum infections and necessity of pain relief. Results:  We randomised 371 women. Mean duration of labour was not significantly different (primiparae: morning 12 hours and 8 minutes versus evening 11 hours and 22 minutes, P value 0.29; multiparae: morning 7 hours and 34 minutes versus evening 7 hours and 46 minutes, P value 0.70). There were no significant differences in instrumental deliveries rates, number of infections or patient satisfaction. Unexpectedly, neonatal outcome was better in women induced in the evening. Conclusion:  Induction of labour with intravenous oxytocin in the evening is equally effective as induction in the morning.-
dc.description.statementofresponsibilityJJ Bakker, R De Vos, M Pel, C Wisman, JM Van Lith, BWJ Mol, JA Van Der Post-
dc.rights© 2009 The Authors-
dc.subjectCircadian rhythm; duration of labour; induced labour; oxytocin-
dc.titleStart of induction of labour with oxytocin in the morning or in the evening. A randomised controlled trial-
dc.typeJournal article-
dc.identifier.orcidMol, B. [0000-0001-8337-550X]-
Appears in Collections:Aurora harvest 7
Obstetrics and Gynaecology publications

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