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Type: Journal article
Title: Antibody to hepatitis B antigen in haemophiliacs and their household contacts
Author: Burrell, C.
Parker, A.
Ramsay, D.
Proudfoot, E.
Citation: Journal of Clinical Pathology, 1974; 27(4):323-325
Publisher: BMJ Publishing Group
Issue Date: 1974
ISSN: 0021-9746
Statement of
C. J. Burrell, A. C. Parker, D. M. Ramsay, Elaine Proudfoot
Abstract: The prevalence of antibody to hepatitis B antigen, detectable by radioimmunoassay, was found to be no higher among 58 long-term household contacts of multiply transfused haemophiliacs than among 100 randomly chosen blood donors. This suggested that such contacts do not have greater exposure to serum hepatitis virus than that occurring through natural means. Among those persons possessing antibody, the multiply transfused haemophiliacs showed a marked tendency for higher antibody titres than their contacts, implying differences in pathogenesis between infection acquired through multiple transfusion and infection acquired naturally.
Keywords: Humans; Hemophilia A; Iodine Radioisotopes; Aspartate Aminotransferases; Immune Sera; Hepatitis B Antibodies; Hepatitis B Antigens; Radioimmunoassay; Family; Blood Donors; Female; Male; Transfusion Reaction
Rights: Copyright status unknown
RMID: 0030010001
DOI: 10.1136/jcp.27.4.323
Appears in Collections:Molecular and Biomedical Science publications

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