Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/8659
Citations | ||
Scopus | Web of ScienceĀ® | Altmetric |
---|---|---|
?
|
?
|
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Mahadevan, I. | - |
dc.contributor.author | Kimber, M. | - |
dc.contributor.author | Lincoln, S. | - |
dc.contributor.author | Tiekink, E. | - |
dc.contributor.author | Ward, A. | - |
dc.contributor.author | Betts, W. | - |
dc.contributor.author | Forbes, I. | - |
dc.contributor.author | Zalewski, P. | - |
dc.date.issued | 1996 | - |
dc.identifier.citation | Australian Journal of Chemistry: an international journal for chemical science, 1996; 49(5):561-568 | - |
dc.identifier.issn | 0004-9425 | - |
dc.identifier.issn | 1445-0038 | - |
dc.identifier.uri | http://hdl.handle.net/2440/8659 | - |
dc.description.abstract | <jats:p>The syntheses of Zinquin ester [ethyl [2-methyl-8-(p- tolylsulfonylamino )-6-quinolyloxy]acetate] and the corresponding acid, both of which are zinc(II)-specific fluorophores , are described. 6-Methoxy-2-methyl-8-(p- tolylsulfonylamino ) quinoline (2) can be demethylated , with boron tribromide, to form either the expected phenol or a mixture of the phenol and the corresponding 5-bromo derivative depending upon the reaction conditions. These compounds react with ethyl bromoacetate to give the corresponding esters, as well as the 5-ethoxycarbonyl derivative formed by electrophilic substitution. Halogenation of the sulfonamide (2) occurs readily at the 5-position. The 5-iodo product undergoes a Heck coupling with ethyl acrylate . The crystal structures of ethyl [5-ethoxycarbonylmethyl-2-methyl-8-(p- tolylsulfonylamino )-6-quinolyloxy]acetate and [5-carboxymethyl-2-methyl-8-(p- tolylsulfonylamino )-6-quinolyloxy]acetic acid are described. </jats:p> | - |
dc.language.iso | en | - |
dc.publisher | CSIRO PUBLISHING | - |
dc.source.uri | http://dx.doi.org/10.1071/ch9960561 | - |
dc.title | The synthesis of zinquin ester and zinquin acid, zinc (II)-specific fluorescing agents for use in the study of biological zinc(ii). | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1071/ch9960561 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Zalewski, P. [0000-0001-5196-2611] | - |
Appears in Collections: | Aurora harvest Environment Institute publications Medicine publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.