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dc.contributor.authorDodd, I.B.-
dc.contributor.authorEgan, J.B.-
dc.identifier.citationNucleic Acids Research, 1990; 18(17):5019-5026-
dc.description.abstractWe present an update of our method for systematic detection and evaluation of potential hellx-turn-helix DNA-binding motifs in protein sequences [Dodd, I. and Egan, J. B. (1987) J. Mol. Biol. 194, 557-564]. The new method is considerably more powerful, detecting approximately 50% more likely hellx-turn-helix sequences without an Increase In false predictions. This improvement is due almost entirely to the use of a much larger reference set of 91 presumed helix-tumhellx sequences. The scoring matrix derived from this reference set has been calibrated against a large protein sequence database so that the score obtained by a sequence can be used to give a practical estimation of the probability that the sequence Is a helix-turn-helix motif.-
dc.description.statementofresponsibilityIan B.Dodd and J.Barry Egan-
dc.publisherOxford University Press-
dc.rights© 1990 Oxford University Press-
dc.subjectDNA-Binding Proteins-
dc.subjectAmino Acid Sequence-
dc.subjectProtein Conformation-
dc.subjectMolecular Sequence Data-
dc.subjectInformation Systems-
dc.titleImproved detection of helix-turn-helix DNA-binding motifs in protein sequences-
dc.typeJournal article-
dc.identifier.orcidDodd, I.B. [0000-0003-2969-6841]-
Appears in Collections:Aurora harvest 7
Molecular and Biomedical Science publications

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