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Type: Journal article
Title: Interstitial lung disease in Sjogren's syndrome
Author: Nikpour, M.
Proudman, S.M.
Goh, N.S.
Moutsopoulos, H.M.
Citation: Current Rheumatology Reviews, 2010; 6(2):127-137
Publisher: Bentham Science Publishers
Issue Date: 2010
ISSN: 1573-3971
Statement of
Mandana Nikpour, Susanna M. Proudman, Nicole S. Goh and Haralampos M. Moutsopoulos
Abstract: Sjogrens syndrome (SS), whether primary, or secondary to other autoimmune rheumatic diseases, is classically associated with the sicca complex of keratoconjunctivits and xerostomia. However, extraglandular manifestations are also relatively common, affecting up to 25% of patients. In this article, we discuss respiratory system involvement in SS, with a focus on interstitial lung disease (ILD). We review the histopathologic variants, clinical features, diagnosis and treatment of SS-ILD. Novel and emerging diagnostic and prognostic biomarkers for SS-ILD are also discussed. We offer an approach to the management of SS-ILD including possible goals of therapy. We conclude by highlighting areas for future research.
Keywords: Sjogren's syndrome; interstitial lung disease; lymphoproliferative
Rights: © 2010 Bentham Science Publishers
RMID: 0030012592
DOI: 10.2174/157339710791330687
Appears in Collections:Medicine publications

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