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Type: Journal article
Title: Network models of phage-bacteria coevolution
Author: Rosvall, M.
Dodd, I.
Krishna, S.
Sneppen, K.
Citation: Physical Review E, 2006; 74(6):066105-1-066105-7
Issue Date: 2006
ISSN: 1539-3755
Statement of
Martin Rosvall, Ian B. Dodd, Sandeep Krishna, and Kim Sneppen
Abstract: Bacteria and their bacteriophages are the most abundant, widespread, and diverse groups of biological entities on the planet. In an attempt to understand how the interactions between bacteria, virulent phages, and temperate phages might affect the diversity of these groups, we developed a stochastic network model for examining the coevolution of these ecologies. In our approach, nodes represent whole species or strains of bacteria or phages, rather than individuals, with “speciation” and extinction modeled by duplication and removal of nodes. Phage-bacteria links represent host-parasite relationships and temperate-virulent phage links denote prophage-encoded resistance. The effect of horizontal transfer of genetic information between strains was also included in the dynamical rules. The observed networks evolved in a highly dynamic fashion but the ecosystems were prone to collapse one or more entire groups going extinct . Diversity could be stably maintained in the model only if the probability of speciation was independent of the diversity. Such an effect could be achieved in real ecosystems if the speciation rate is primarily set by the availability of ecological niches.
Rights: © 2006 The American Physical Society
RMID: 0030013113
DOI: 10.1103/PhysRevE.74.066105
Appears in Collections:Molecular and Biomedical Science publications

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