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Type: Patent
Title: Systematic evolution of ligands by exponential enrichment: tissue selex
Author: Jensen, K.
Chen, H.
Morris, K.N.
Stephens, A.
Gold, L.
Issue Date: 1999
Assignee: NeXstar Pharmaceuticals, Inc.
Statement of
Inventors: Jensen Kirk, Chen Hang, Morris Kevin N., Stephens Andrew, Gold Larry. Assignee: NeXstar Pharmaceuticals, Inc. Agents: Swanson & Bratschun LLC
Abstract: This invention discloses high-affinity oligonucleotide ligands to complex tissue targets, specifically nucleic acid ligands having the ability to bind to complex tissue targets, and the methods for obtaining such ligands. Tissue targets comprise cells, subcellular components, aggregates or cells, collections of cells, and higher ordered structures. Specifically, nucleic acid ligands to red blood cells ghosts, glioblastomas, and lymphomas are described.
Description: Publication number US5864026 A Publication type Grant Application number US 08/437,667 Publication date Jan 26, 1999 Filing date May 3, 1995 Priority date Jun 11, 1990
Patent #: US5864026
RMID: 0030016585
Appears in Collections:Molecular and Biomedical Science publications

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