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Type: Patent
Title: Systematic evolution of ligands by exponential enrichment: tissue SELEX
Author: Jensen, K.B.
Chen, H.
Morris, K.N.
Stephens, A.
Gold, L.
Issue Date: 1998
Assignee: Swanson & Bratschun LLC
Statement of
Inventors: Jensen Kirk, Chen Hang, Morris Kevin N., Stephens Andrew, Gold Larry. Assignee: NeXstar Pharmaceuticals, Inc. Agents: Swanson & Bratschun LLC
Abstract: This invention discloses high-affinity oligonucleotide ligands to complex tissue targets, specifically nucleic acid ligands having the ability to bind to complex tissue targets, and the methods for obtaining such ligands. Tissue targets comprise cells, subcellular components, aggregates or cells, collections of cells, and higher ordered structures. Specifically, nucleic acid ligands to red blood cells ghosts, glioblastomas, and lymphomas are described.
Description: Publication number US5763566 A Publication type Grant Application number US 08/433,585 Publication date Jun 9, 1998 Filing date May 3, 1995 Priority date Jun 11, 1990
Patent #: US5763566
Published version:
Appears in Collections:Aurora harvest 7
Molecular and Biomedical Science publications

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