Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/87902
Type: | Patent |
Title: | Systematic evolution of ligands by exponential enrichment: Chemi-SELEX |
Author: | Gold, L. Eaton, B. Smith, D. Wecker, M. Jensen, K. |
Issue Date: | 1999 |
Assignee: | NeXstar Pharmaceuticals, Inc. |
Statement of Responsibility: | Inventors: Larry Gold, Bruce Eaton, Drew Smith, Matthew Wecker, Kirk Jensen. Assignee: NeXstar Pharmaceuticals, Inc. Agents: Swanson & Bratschun LLC |
Abstract: | This application provides methods for identifying nucleic acid ligands capable of covalently interacting with targets of interest. The nucleic acids can be associated with various functional units. The method also allows for the identification of nucleic acids that have facilitating activities as measured by their ability to facilitate formation of a covalent bond between the nucleic acid, including its associated functional unit, and its target. |
Description: | Publication number US5998142 A Publication type Grant Application number US 08/894,578 Publication date Dec 7, 1999 Filing date Aug 21, 1997 Priority date Sep 8, 1993 |
Patent #: | US5998142 |
Appears in Collections: | Aurora harvest 2 Molecular and Biomedical Science publications |
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