Please use this identifier to cite or link to this item:
|Scopus||Web of Science®||Altmetric|
|Title:||Adherence and motility characteristics of clinical Acinetobacter baumannii isolates|
|Citation:||FEMS Microbiology Letters, 2011; 323(1):44-51|
|Bart A. Eijkelkamp, Uwe H. Stroeher, Karl A. Hassan, Michael S. Papadimitrious, Ian T. Paulsen, and Melissa H. Brown|
|Abstract:||Acinetobacter baumannii continues to be a major health problem especially in hospital settings. Herein, features that may play a role in persistence and disease potential were investigated in a collection of clinical A. baumannii strains from Australia. Twitching motility was found to be a common trait in A. baumannii international clone I strains and in abundant biofilm formers, whereas swarming motility was only observed in isolates not classified within the international clone lineages. Bioinformatic analysis of the type IV fimbriae revealed a correlation between PilA sequence homology and motility. A high level of variability in adherence to both abiotic surfaces and epithelial cells was found. We report for the first time the motility characteristics of a large number of A. baumannii isolates and present a direct comparison of A. baumannii binding to nasopharyngeal and lung epithelial cells.|
|Keywords:||twitching; swarming; eukaryotic cell adherence; biofilm formation; type IV pili; Australian clinical strains|
|Rights:||© 2011 Federation of European Microbiological Societies|
|Appears in Collections:||Molecular and Biomedical Science publications|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.