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Type: Journal article
Title: Vitamin D in preterm infants: a prospective observational study
Author: Pinto, K.
Collins, C.
Gibson, R.
Andersen, C.
Citation: Journal of Paediatrics and Child Health, 2015; 51(7):679-681
Publisher: Wiley
Issue Date: 2015
ISSN: 1034-4810
Statement of
Kieran Pinto, Carmel T Collins, Robert A Gibson, and Chad C Andersen
Abstract: AIM: Preterm infants are at increased risk of vitamin D deficiency as a result of both maternal deficiency and inadequate supplementation. The quantity and effectiveness of vitamin D supplementation in preterm infants are unclear. The aim of this study was to evaluate the natural history of vitamin D status in preterm infants and the effectiveness of the hospital's nutritional practices in meeting current supplementation recommendations. METHODS: A prospective observational study was undertaken in the Neonatal Unit at the Women's and Children's Hospital, Adelaide. Enrolled infants received a standardised nutrition protocol with emphasis on vitamin D supplementation. The main outcome measure was a comparison of the proportion of vitamin D-deficient infants (25(OH)D < 50 nmol/L) at birth versus 36 weeks post-menstrual age/discharge. RESULTS: Twenty-eight infants born between 30 and 36 weeks gestation were enrolled. The proportion of vitamin D-deficient infants decreased from initial to final measurement (32.1% vs. 7.1%, P = 0.016), whereas mean (standard deviation) 25(OH)D3 increased over the same period (58.4 (18.4) vs. 82.9 (29.2) nmol/L, P < 0.001). Mean vitamin D intake was 643.6 (285.3) IU/day. CONCLUSIONS: Current nutritional practices are effective in meeting recommendations regarding vitamin D intake and result in a lower proportion of deficient infants at 36 weeks post-menstrual age/discharge.
Keywords: neonatology; nutrition; preterm; vitamin D
Rights: © 2015 The Authors
RMID: 0030022830
DOI: 10.1111/jpc.12847
Grant ID:
Appears in Collections:Paediatrics publications

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