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https://hdl.handle.net/2440/91492
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dc.contributor.author | Mahal, B. | - |
dc.contributor.author | Ziehr, D. | - |
dc.contributor.author | Aizer, A. | - |
dc.contributor.author | Hyatt, A. | - |
dc.contributor.author | Lago-Hernandez, C. | - |
dc.contributor.author | Choueiri, T. | - |
dc.contributor.author | Elfiky, A. | - |
dc.contributor.author | Hu, J. | - |
dc.contributor.author | Sweeney, C. | - |
dc.contributor.author | Beard, C. | - |
dc.contributor.author | D'Amico, A. | - |
dc.contributor.author | Martin, N. | - |
dc.contributor.author | Kim, S. | - |
dc.contributor.author | Lathan, C. | - |
dc.contributor.author | Trinh, Q. | - |
dc.contributor.author | Nguyen, P. | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | Journal of Geriatric Oncology, 2014; 5(4):352-358 | - |
dc.identifier.issn | 1879-4068 | - |
dc.identifier.issn | 1879-4076 | - |
dc.identifier.uri | http://hdl.handle.net/2440/91492 | - |
dc.description.abstract | PURPOSE: To evaluate the relationship between age and race on the receipt of definitive therapy among men with high-risk prostate cancer (CaP). METHODS: We used the Surveillance, Epidemiology and End Results Program to identify 62,644 men with high-risk CaP (PSA >20 or Gleason 8-10 or stage ≥cT3a) diagnosed from 2004 to 2010. Multivariable logistic regression analysis modeled the interaction between age and race and its association with receipt of definitive therapy on 57,674 patients (47,879 white men; 9,795 African American [AA] men) with complete data on the covariates of interest. RESULTS: Among men age ≥70, AA men had a higher risk of CaP-specific mortality (PCSM) compared to white men after adjusting for sociodemographic and prostate cancer-specific factors (Adjusted HR 1.20; 95% CI 1.02-1.38; P=0.02). Nevertheless, a significant interaction between race and age was found (Pinteraction=0.01), such that the adjusted odds of receiving definitive treatment for AA vs. white was 0.67 (95% CI 0.62-0.73; P<0.001) among men age <70, but was 0.60 (95% CI 0.55-0.66; P<0.001) among men age ≥70, suggesting increased racial disparity in the receipt of definitive treatment among older men. CONCLUSION: AA men with high-risk CaP are less likely to receive definitive therapy than white men. This disparity is significantly larger among men age ≥70, despite excess PCSM among AA men in this group. With a rapidly expanding population of older minority men, this disparity should be urgently addressed to prevent increasing disparities in cancer care. | - |
dc.description.statementofresponsibility | Brandon A. Mahal, David R. Ziehr, Ayal A. Aizer, Andrew S. Hyatt, Carlos Lago-Hernandez, Toni K. Choueiri, Aymen A. Elfiky, Jim C. Hu, Christopher J. Sweeney, Clair J. Beard, Anthony V. D, Amico, Neil E. Martin, Simon P. Kim, Christopher S. Lathan, Quoc-Dien Trinh, Paul L. Nguyen | - |
dc.language.iso | en | - |
dc.publisher | Elsevier | - |
dc.rights | © 2014 Elsevier Inc. All rights reserved. | - |
dc.source.uri | http://dx.doi.org/10.1016/j.jgo.2014.05.001 | - |
dc.subject | African American | - |
dc.subject | Geriatrics | - |
dc.subject | Healthcare disparities | - |
dc.subject | Population health | - |
dc.subject | Prostatic neoplasms | - |
dc.title | Racial disparities in an aging population: the relationship between age and race in the management of African American men with high-risk prostate cancer | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1016/j.jgo.2014.05.001 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Sweeney, C. [0000-0002-0398-6018] | - |
Appears in Collections: | Aurora harvest 2 Medicine publications |
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