Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/9153
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Type: Journal article
Title: The five year reproducibility of calcium-related biochemical variables in postmenopausal women
Author: Morris, H.
Cleghorn, D.
Need, A.
Horowitz, M.
Nordin, B.
Citation: Scandinavian Journal of Laboratory and Clinical Medicine, 1995; 55(5):383-389
Publisher: Informa Healthcare
Issue Date: 1995
ISSN: 0036-5513
1502-7686
Statement of
Responsibility: 
H. A. Morris, D. B. Cleghorn, A. G. Need, M. Horowitz and B. E. C. Nordin
Abstract: A total of 19 measured and derived bone-related biochemical variables were determined in 307 postmenopausal volunteers on two occasions, 5 years apart. The plasma variables with the highest coefficients of determination (r2) were plasma globulins, alkaline phosphatase, creatinine and calculated ionized and ultrafiltrable calcium. In the urine, the highest r2 values were in respect of fasting urine calcium excretion corrected for urine sodium, hydroxyproline excretion, and the maximal renal tubular reabsorption of calcium and phosphate (TmCa/GFR and TmP/GFR). The components of variance of TmCa/GFR and TmP/GFR show marked individuality but their methods determination meet the criterion for acceptable analytical goals. We conclude that most of the measured and derived bone-related biochemical variables in fasting plasma and urine are sufficiently reproducible in postmenopausal women to be useful for ranking individuals for a period up to 5 years.
Keywords: Biochemistry, bone markers, menopause, reproducibility
Rights: Copyright status unknown
RMID: 0030004749
DOI: 10.3109/00365519509104977
Appears in Collections:Medicine publications

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