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Type: Journal article
Title: First human case of fatal Halicephalobus gingivalis meningoencephalitis in Australia
Author: Lim, C.
Crawford, A.
Moore, C.
Gasser, R.
Nelson, R.
Koehler, A.
Bradbury, R.
Speare, R.
Dhatrak, D.
Weldhagen, G.
Citation: Journal of Clinical Microbiology, 2015; 53(5):1768-1774
Publisher: American Society for Microbiology
Issue Date: 2015
ISSN: 0095-1137
Statement of
Chuan Kok Lim, April Crawford, Casey V. Moore, Robin B. Gasser, Renjy Nelson, Anson V. Koehler, Richard S. Bradbury, Rick Speare, Deepak Dhatrak, Gerhard. F. Weldhagen
Abstract: Halicephalobus gingivalis (previously Micronema deletrix) is a free-living nematode known to cause opportunistic infections, mainly in horses. Human infections are very rare, but all cases described to date involved fatal meningoencephalitis. Here we report the first case of H. gingivalis infection in an Australian human patient, confirmed by nematode morphology and sequencing of ribosomal DNA. The implications of this case are discussed, particularly, the need to evaluate real-time PCR as a diagnostic tool.
Keywords: Brain; Animals; Humans; Rhabditida; Rhabditida Infections; Meningoencephalitis; DNA, Ribosomal; Microscopy; Histocytochemistry; Sequence Analysis, DNA; Molecular Sequence Data; Aged; Australia; Female
Rights: Copyright © 2015, American Society for Microbiology. All Rights Reserved.
RMID: 0030022636
DOI: 10.1128/JCM.00032-15
Appears in Collections:Medicine publications

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