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|Title:||First human case of fatal Halicephalobus gingivalis meningoencephalitis in Australia|
|Citation:||Journal of Clinical Microbiology, 2015; 53(5):1768-1774|
|Publisher:||American Society for Microbiology|
|Chuan Kok Lim, April Crawford, Casey V. Moore, Robin B. Gasser, Renjy Nelson, Anson V. Koehler, Richard S. Bradbury, Rick Speare, Deepak Dhatrak, Gerhard. F. Weldhagen|
|Abstract:||Halicephalobus gingivalis (previously Micronema deletrix) is a free-living nematode known to cause opportunistic infections, mainly in horses. Human infections are very rare, but all cases described to date involved fatal meningoencephalitis. Here we report the first case of H. gingivalis infection in an Australian human patient, confirmed by nematode morphology and sequencing of ribosomal DNA. The implications of this case are discussed, particularly, the need to evaluate real-time PCR as a diagnostic tool.|
|Keywords:||Brain; Animals; Humans; Rhabditida; Rhabditida Infections; Meningoencephalitis; DNA, Ribosomal; Microscopy; Histocytochemistry; Sequence Analysis, DNA; Molecular Sequence Data; Aged; Australia; Female|
|Rights:||Copyright © 2015, American Society for Microbiology. All Rights Reserved.|
|Appears in Collections:||Medicine publications|
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