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Type: Journal article
Title: Leptospirosis in American Samoa 2010: epidemiology, environmental drivers, and the management of emergence
Author: Lau, C.
Dobson, A.
Smythe, L.
Fearnley, E.
Skelly, C.
Clements, A.
Craig, S.
Fuimaono, S.
Weinstein, P.
Citation: American Journal of Tropical Medicine and Hygiene, 2012; 86(2):309-319
Publisher: American Society of Tropical Medicine and Hygiene
Issue Date: 2012
ISSN: 0002-9637
Statement of
Colleen L. Lau, Annette J. Dobson, Lee D. Smythe, Emily J. Fearnley, Chris Skelly, Archie C. A. Clements, Scott B. Craig, Saipale D. Fuimaono, and Philip Weinstein
Abstract: Leptospirosis has recently been reported as an emerging disease worldwide, and a seroprevalence study was undertaken in American Samoa to better understand the drivers of transmission. Antibodies indicative of previous exposure to leptospirosis were found in 15.5% of 807 participants, predominantly against three serovars that were not previously known to occur in American Samoa. Questionnaires and geographic information systems data were used to assess behavioral factors and environmental determinants of disease transmission, and logistic regression was used to identify factors associated with infection. Many statistically significant factors were consistent with previous studies, but we also showed a significant association with living at lower altitudes (odds ratio [OR] = 1.53, 95% confidence interval [CI]: 1.03-2.28), and having higher numbers of piggeries around the home (OR = 2.63, 95% CI: 1.52-4.40). Our findings support a multifaceted approach to combating the emergence of leptospirosis, including modification of individual behavior, but importantly also managing the evolving environmental drivers of risk.
Keywords: Humans
Rights: Copyright © 2012 by The American Society of Tropical Medicine and Hygiene
RMID: 0030024671
DOI: 10.4269/ajtmh.2012.11-0398
Appears in Collections:Public Health publications

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