Please use this identifier to cite or link to this item:
|Scopus||Web of Science®||Altmetric|
|Title:||Metabolic syndrome, cognitive performance, and dementia|
|Citation:||Journal of Alzheimer's Disease, 2012; 30(S2):S77-S87|
|Georgina E. Crichton, Merrill F. Elias, Jonathan D. Buckley, Karen J. Murphy, Janet Bryan and Vincenza Frisardi|
|Abstract:||Obesity, hypertension, dyslipidemia, and insulin resistance have been associated with an increased risk of cognitive impairment or dementia. Together, these risk factors cluster as metabolic syndrome (MetS). The first aim of this systematic review was to identify and critically review studies assessing associations between MetS and cognition, with consideration given both to early cognitive changes and the severe endpoint of dementia. The second aim was to identify and discuss limitations in the literature and subsequent difficulties in drawing conclusions from research to date. Nine studies that assessed cognitive performance and ten studies that estimated incidence of dementia in relation to MetS were identified and appraised. Limitations in the literature include the lack of standardized nomenclature for cognitive variables, the use of multiple MetS definitions, and the difficulty in differentiating the adverse effects of multiple risk factors on cognition.|
|Rights:||© 2012 – IOS Press and the authors. All rights reserved.|
|Appears in Collections:||Aurora harvest 7|
Molecular and Biomedical Science publications
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.