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Type: Journal article
Title: Structural and functional remodeling of the left atrium: clinical and therapeutic implications for atrial fibrillation
Author: Pathak, R.
Lau, D.H.
Mahajan, R.
Sanders, P.
Citation: Journal of Atrial Fibrillation, 2013; 6(4):53-64
Publisher: CardioFront
Issue Date: 2013
ISSN: 1941-6911
Statement of
Rajeev Pathak, Dennis H. Lau, Rajiv Mahajan, Prashanthan Sanders
Abstract: Atrial fibrillation (AF) is the most commonly encountered arrhythmia in clinical practice. Despite advances in our understanding of the pathophysiology of this complex arrhythmia, current therapeutic options remain suboptimal. This review aimed to delineate the atrial structural and functional remodeling leading to the perpetuation of AF. We explored the complex changes seen in the atria in various substrates for AF and the therapeutic options available to prevent these changes or for reverse remodeling. Here we also highlighted the emerging role of aggressive risk factor management aimed at the arrhythmogenic atrial substrate to prevent or retard AF progression.
Rights: Copyright status unknown
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