Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/93761
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Type: Journal article
Title: Change in quality of life after transcatheter aortic valve implantation and aortic valve replacement surgery in Australian patients aged ≥ 75 years: the effects of EuroSCORE and patient operability
Other Titles: Change in quality of life after transcatheter aortic valve implantation and aortic valve replacement surgery in Australian patients aged >/- 75 years: the effects of EuroSCORE and patient operability
Author: Tully, P.
Roshan, P.
Rice, G.
Sinhal, A.
Bennetts, J.
Baker, R.
Citation: Journal of Geriatric Cardiology, 2015; 12(1):30-36
Publisher: Science Press
Issue Date: 2015
ISSN: 1671-5411
Statement of
Responsibility: 
Phillip J Tully, Prakash Roshan, Greg D Rice, Ajay Sinhal, Jayme S Bennetts, Robert A Baker
Abstract: OBJECTIVE: To determine the extent to which differences in generic quality of life (QOL) between transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (AVR) patients explained by EuroSCORE and heart-team operability assessment. METHODS: A total of 146 high-risk patients with EuroSCORE > 6 and aged ≥ 75 years underwent TAVI (n = 80) or aortic valve replacement (n = 66) between February 2010 and July 2013. A total of 75 patients also completed preoperative and six month SF-12 QOL measures. Analyses examined incident major morbidity, compared six month QOL between groups adjusted for EuroSCORE and operability, and quantified rates of clinically significant QOL improvement and deterioration. RESULTS: The AVR group required longer ventilation (> 24 h) (TAVI 5.0% vs. AVR 20.6%, P = 0.004) and more units of red blood cells [TAVI 0 (0-1) vs. AVR 2 (0-3), P = 0.01]. New renal failure was higher in TAVI (TAVI 5.0% vs. AVR 0%, P = 0.06). TAVI patients reported significantly lower vitality (P = 0.01) by comparison to AVR patients, however these findings were no longer significant after adjustment for operability. In both procedures, clinically significant QOL improvement was common [range 25.0% (general health) - 62.9% (physical role)] whereas deterioration in QOL occurred less frequently [range 9.3% (physical role) - 33.3% (mental health)]. CONCLUSIONS: Clinically significant improvement and deterioration in QOL was evident at six months in high risk elderly aortic valve replacement patients. Overall QOL did not differ between TAVI and AVR once operability was taken into consideration.
Keywords: Aortic valve replacement; Cardiac surgery; EuroSCORE; Quality of life; Transcatheter aortic valve implantation
Description: Research article
Rights: Copyright status unknown. Open access
RMID: 0030022639
DOI: 10.11909/j.issn.1671-5411.2015.01.004
Grant ID: http://purl.org/au-research/grants/nhmrc/1053578
Appears in Collections:Medicine publications

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