Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/93967
Citations
Scopus Web of Science® Altmetric
?
?
Type: Journal article
Title: What factors impact upon a woman's decision to undertake genetic cancer testing?
Author: Quinlivan, J.A.
Battikhi, Z.
Petersen, R.W.
Citation: Frontiers in Oncology, 2014; 3:325-1-325-6
Publisher: Frontiers
Issue Date: 2014
ISSN: 2234-943X
2234-943X
Statement of
Responsibility: 
Julie A. Quinlivan, Zain Battikhi and Rodney W. Petersen
Abstract: Introduction: The advent of human genome project has lead to genetic tests that identify high-risk states for certain cancers. Many are privately marketed on the Internet. Despite the availability of tests, limited data has evaluated factors that lead to test uptake. The aim of the present study was to explore the attitudes of a cohort of new mothers toward uptake of a genetic cancer test with a 50% predictive value of cancer. Methods: A cross-sectional survey was undertaken. The project targeted women who had recently given birth at an Australian tertiary referral hospital. Women were asked about a theoretical blood test that detected an increased risk for the development of cancer. Attitudes and knowledge questionnaires were completed. Results: Of 232 consecutive women approached, 32 declined, giving a response rate of 86.2%. Only 63 (31.5%) women stated they would have the test. Absence of religious belief, higher level of education, better knowledge of terms used in genetics, an absence of concern over emotional, employment, and insurance discrimination, and previous acceptance of Down syndrome screening in pregnancy were each associated with significantly higher rate of test uptake in univariate analysis (all p < 0.03). In multivariate analysis, a lack of concern over discrimination and a history of having accepted Down syndrome screening in the previous pregnancy remained significantly associated with test uptake (all p < 0.0001). Conclusion: Concern over discrimination and having made a prior decision to have genetic testing were the principal factors associated with decision-making.
Keywords: breast cancer; genetic cancer screening; pregnancy; discrimination; ethics; education
Rights: © 2014 Quinlivan, Battikhi and Petersen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
DOI: 10.3389/fonc.2013.00325
Appears in Collections:Aurora harvest 7
Paediatrics publications

Files in This Item:
File Description SizeFormat 
hdl_93967.pdfPublished version455.32 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.