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|Title:||Predictors of delayed gastric emptying in diabetes|
|Citation:||Diabetes Care, 2001; 24(7):1264-1269|
|Publisher:||Amer Diabetes Assoc|
|Karen L. Jones, Antonietta Russo, Julie E. Stevens, Judith M. Wishart, Melanie K. Berry And Michael Horowitz.|
|Abstract:||Objective — To define the predictors of the rate of gastric emptying in patients with diabetes. Research design and methods — A total of 101 outpatients with diabetes (79 type 1 and 22 type 2) underwent measurements of gastric emptying of a solid/liquid meal (scintigraphy), upper gastrointestinal symptoms (questionnaire), glycemic control (blood glucose concentrations during gastric emptying measurement), and autonomic nerve function (cardiovascular reflexes). Results— The gastric emptying of solid and/or liquid was delayed in 66 (65%) patients. Solid (retention at 100 min 64 6 3.2 vs. 50.2 6 3.6%, P , 0.005) and liquid (retention at 100 min 22.761.7 vs. 16.061.8%, P,0.001) gastric emptying was slower in women than in men. Of all upper gastrointestinal symptoms (including nausea and vomiting), only abdominal bloating/ fullness was associated with slower gastric emptying (P , 0.005). A multiple regression analysis demonstrated that both abdominal bloating/fullness and female sex were predictors of slower gastric emptying of both solids and liquids. Conclusions — We conclude that the presence of abdominal bloating/fullness but not any other upper gastrointestinal symptom is associated with diabetic gastroparesis and that gastric emptying is slower in diabetic women than in diabetic men.|
|Keywords:||Autonomic Nervous System; Animals; Cattle; Humans; Gastrointestinal Diseases; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Blood Glucose; Questionnaires; Blood Pressure; Heart Rate; Systole; Gastric Emptying; Meat; Middle Aged; Outpatients|
|Rights:||Copyright © 2001 American Diabetes Association|
|Appears in Collections:||Medicine publications|
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