Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/94426
Citations
Scopus Web of Science® Altmetric
?
?
Full metadata record
DC FieldValueLanguage
dc.contributor.authorTully, P.-
dc.contributor.authorCosh, S.-
dc.contributor.authorBaumeister, H.-
dc.date.issued2014-
dc.identifier.citationJournal of Psychosomatic Research, 2014; 77(6):439-448-
dc.identifier.issn0022-3999-
dc.identifier.issn1879-1360-
dc.identifier.urihttp://hdl.handle.net/2440/94426-
dc.description.abstractOBJECTIVE: To (1) report the prognostic association between anxiety disorder subtypes and major adverse cardiac events (MACE), (2) report anxiety disorder prevalence in coronary heart disease (CHD), and (3) report the efficacy of anxiety disorder treatments in CHD. METHODS: A comprehensive electronic database search was performed in November 2013 for studies reporting anxiety disorder prevalence according to structured interview in CHD samples or MACE, and randomized controlled trials (RCTs) comparing anxiety disorder treatment with placebo or usual care. From 4041 articles 42 samples were selected for extraction (8 for MACE prognosis, 39 for prevalence, no RCTs were eligible). RESULTS: Five generalized anxiety disorder (GAD) studies reported 883 MACE events (combined n=2851). There was a non-significant association between GAD and MACE (risk ratio=1.20, 95% CI .86-1.68, P=.28) however the effect size was highly significant in outpatient samples (adjusted hazard ratio=1.94, 95% CI 1.45-2.60, P<.001). No other anxiety disorder subtype was associated with MACE. Prevalence data showed high comorbidity with depression (49.06%; 95% CI 34.28-64.01) and substantial heterogeneity between studies. Panic disorder prevalence was higher in psychiatrist/psychologist raters (9.92% vs. 4.74%) as was GAD (18.45% vs. 13.01%). Panic and GAD estimates were also heterogeneous according to DSM-III-R versus DSM-IV taxonomies. CONCLUSIONS: The paucity of extant anxiety disorder RCTs, alongside MACE risk for GAD outpatients, should stimulate further anxiety disorder intervention in CHD populations. Research should focus on depression and anxiety, thereby unraveling disorder specific and more generic pathways.-
dc.description.statementofresponsibilityPhillip J. Tully, Suzanne M. Cosh, Harald Baumeister-
dc.language.isoen-
dc.publisherElsevier-
dc.rights© 2014 Elsevier Inc. All rights reserved.-
dc.source.urihttp://dx.doi.org/10.1016/j.jpsychores.2014.10.001-
dc.subjectAnxiety Disorder-
dc.subjectCoronary heart disease-
dc.subjectMeta-analysis-
dc.subjectMeta-regression-
dc.subjectPrognosis-
dc.subjectDiagnosis-
dc.titleThe anxious heart in whose mind? A systematic review and meta-regression of factors associated with anxiety disorder diagnosis, treatment and morbidity risk in coronary heart disease-
dc.typeJournal article-
dc.identifier.doi10.1016/j.jpsychores.2014.10.001-
dc.relation.granthttp://purl.org/au-research/grants/nhmrc/1053578-
pubs.publication-statusPublished-
dc.identifier.orcidTully, P. [0000-0003-2807-1313]-
dc.identifier.orcidCosh, S. [0000-0002-8003-3704]-
Appears in Collections:Aurora harvest 3
Medicine publications

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.