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|dc.identifier.citation||United European Gastroenterology Journal, 2014; 2(3):173-178||-|
|dc.description.abstract||BACKGROUND: Symptomatically 'silent' gastro-oesophageal reflux disease (GORD) may be underdiagnosed. OBJECTIVE: To determine the prevalence of untreated GORD without heartburn and/or regurgitation in primary care. METHODS: Patients were included if they had frequent upper gastrointestinal symptoms and had not taken a proton pump inhibitor in the previous 2 months (Diamond study: NCT00291746). GORD was diagnosed based on the presence of reflux oesophagitis, pathological oesophageal acid exposure, and/or a positive symptom-acid association probability. Patients completed the Reflux Disease Questionnaire (RDQ) and were interviewed by physicians using a prespecified symptom checklist. RESULTS: GORD was diagnosed in 197 of 336 patients investigated. Heartburn and/or regurgitation were reported in 84.3% of patients with GORD during the physician interviews and in 93.4% of patients with GORD when using the RDQ. Of patients with heartburn and/or regurgitation not identified at physician interview, 58.1% (18/31) reported them at a 'troublesome' frequency and severity on the RDQ. Nine patients with GORD did not report heartburn or regurgitation either at interview or on the RDQ. CONCLUSIONS: Structured patient-completed questionnaires may help to identify patients with GORD not identified during physician interview. In a small proportion of consulting patients, heartburn and regurgitation may not be present in those with GORD.||-|
|dc.description.statementofresponsibility||Nimish Vakil, Börje Wernersson, Lis Ohlsson, John Dent||-|
|dc.rights||© Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav||-|
|dc.subject||gastro-oesophageal reflux disease||-|
|dc.subject||oesophageal pH monitoring||-|
|dc.subject||upper abdominal pain||-|
|dc.title||Prevalence of gastro-oesophageal reflux disease with upper gastrointestinal symptoms without heartburn and regurgitation||-|
|Appears in Collections:||Aurora harvest 7|
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