Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/94553
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dc.contributor.authorVakil, N.-
dc.contributor.authorWernersson, B.-
dc.contributor.authorOhlsson, L.-
dc.contributor.authorDent, J.-
dc.date.issued2014-
dc.identifier.citationUnited European Gastroenterology Journal, 2014; 2(3):173-178-
dc.identifier.issn2050-6406-
dc.identifier.issn2050-6414-
dc.identifier.urihttp://hdl.handle.net/2440/94553-
dc.description.abstractBACKGROUND: Symptomatically 'silent' gastro-oesophageal reflux disease (GORD) may be underdiagnosed. OBJECTIVE: To determine the prevalence of untreated GORD without heartburn and/or regurgitation in primary care. METHODS: Patients were included if they had frequent upper gastrointestinal symptoms and had not taken a proton pump inhibitor in the previous 2 months (Diamond study: NCT00291746). GORD was diagnosed based on the presence of reflux oesophagitis, pathological oesophageal acid exposure, and/or a positive symptom-acid association probability. Patients completed the Reflux Disease Questionnaire (RDQ) and were interviewed by physicians using a prespecified symptom checklist. RESULTS: GORD was diagnosed in 197 of 336 patients investigated. Heartburn and/or regurgitation were reported in 84.3% of patients with GORD during the physician interviews and in 93.4% of patients with GORD when using the RDQ. Of patients with heartburn and/or regurgitation not identified at physician interview, 58.1% (18/31) reported them at a 'troublesome' frequency and severity on the RDQ. Nine patients with GORD did not report heartburn or regurgitation either at interview or on the RDQ. CONCLUSIONS: Structured patient-completed questionnaires may help to identify patients with GORD not identified during physician interview. In a small proportion of consulting patients, heartburn and regurgitation may not be present in those with GORD.-
dc.description.statementofresponsibilityNimish Vakil, Börje Wernersson, Lis Ohlsson, John Dent-
dc.language.isoen-
dc.publisherSAGE Publications-
dc.rights© Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav-
dc.subjectBloating-
dc.subjectgastro-oesophageal reflux disease-
dc.subjectheartburn-
dc.subjectoesophageal endoscopy-
dc.subjectoesophageal pH monitoring-
dc.subjectregurgitation-
dc.subjectupper abdominal pain-
dc.titlePrevalence of gastro-oesophageal reflux disease with upper gastrointestinal symptoms without heartburn and regurgitation-
dc.typeJournal article-
dc.identifier.doi10.1177/2050640614532458-
pubs.publication-statusPublished-
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