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https://hdl.handle.net/2440/94553
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dc.contributor.author | Vakil, N. | - |
dc.contributor.author | Wernersson, B. | - |
dc.contributor.author | Ohlsson, L. | - |
dc.contributor.author | Dent, J. | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | United European Gastroenterology Journal, 2014; 2(3):173-178 | - |
dc.identifier.issn | 2050-6406 | - |
dc.identifier.issn | 2050-6414 | - |
dc.identifier.uri | http://hdl.handle.net/2440/94553 | - |
dc.description.abstract | BACKGROUND: Symptomatically 'silent' gastro-oesophageal reflux disease (GORD) may be underdiagnosed. OBJECTIVE: To determine the prevalence of untreated GORD without heartburn and/or regurgitation in primary care. METHODS: Patients were included if they had frequent upper gastrointestinal symptoms and had not taken a proton pump inhibitor in the previous 2 months (Diamond study: NCT00291746). GORD was diagnosed based on the presence of reflux oesophagitis, pathological oesophageal acid exposure, and/or a positive symptom-acid association probability. Patients completed the Reflux Disease Questionnaire (RDQ) and were interviewed by physicians using a prespecified symptom checklist. RESULTS: GORD was diagnosed in 197 of 336 patients investigated. Heartburn and/or regurgitation were reported in 84.3% of patients with GORD during the physician interviews and in 93.4% of patients with GORD when using the RDQ. Of patients with heartburn and/or regurgitation not identified at physician interview, 58.1% (18/31) reported them at a 'troublesome' frequency and severity on the RDQ. Nine patients with GORD did not report heartburn or regurgitation either at interview or on the RDQ. CONCLUSIONS: Structured patient-completed questionnaires may help to identify patients with GORD not identified during physician interview. In a small proportion of consulting patients, heartburn and regurgitation may not be present in those with GORD. | - |
dc.description.statementofresponsibility | Nimish Vakil, Börje Wernersson, Lis Ohlsson, John Dent | - |
dc.language.iso | en | - |
dc.publisher | SAGE Publications | - |
dc.rights | © Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav | - |
dc.source.uri | http://dx.doi.org/10.1177/2050640614532458 | - |
dc.subject | Bloating | - |
dc.subject | gastro-oesophageal reflux disease | - |
dc.subject | heartburn | - |
dc.subject | oesophageal endoscopy | - |
dc.subject | oesophageal pH monitoring | - |
dc.subject | regurgitation | - |
dc.subject | upper abdominal pain | - |
dc.title | Prevalence of gastro-oesophageal reflux disease with upper gastrointestinal symptoms without heartburn and regurgitation | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1177/2050640614532458 | - |
pubs.publication-status | Published | - |
Appears in Collections: | Aurora harvest 7 Medicine publications |
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