Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/95422
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Type: Journal article
Title: Lowering triglycerides to modify cardiovascular risk: will icosapent deliver?
Author: Scherer, D.
Nicholls, S.
Citation: Vascular Health and Risk Management, 2015; 11:203-209
Publisher: Dove Press Ltd.
Issue Date: 2015
ISSN: 1176-6344
1178-2048
Statement of
Responsibility: 
Daniel J Scherer, Stephen J Nicholls
Abstract: Despite the clinical benefits of lowering levels of low-density lipoprotein cholesterol, many patients continue to experience cardiovascular events. This residual risk suggests that additional risk factors require aggressive modification to result in more effective prevention of cardiovascular disease. Hypertriglyceridemia has presented a considerable challenge with regard to understanding its role in the promotion of cardiovascular risk. Increasing evidence has established a clear causal role for elevated triglyceride levels in vascular risk. As a result, there is increasing interest in the development of specific therapeutic strategies that directly target hypertriglyceridemia. This has seen a resurgence in the use of omega-3 fatty acids for the therapeutic lowering of triglyceride levels. The role of these agents and other emerging strategies to reduce triglyceride levels in order to decrease vascular risk are reviewed.
Keywords: Hypertriglyceridemia; omega-3 fatty acid; fish oil; cardiovascular risk; lipids
Rights: © 2015 Scherer and Nicholls. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at: http://www.dovepress.com/permissions.php
DOI: 10.2147/VHRM.S40134
Appears in Collections:Aurora harvest 7
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