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|Title:||Isolation of a human homolog of osteoclast inhibitory lectin that inhibits the formation and function of osteoclasts|
|Citation:||Journal of Bone and Mineral Research, 2004; 19(1):89-99|
|Publisher:||Amer Soc Bone & Mineral Res|
|Yun Shan Hu, Hong Zhou, Damian Myers, Julian M W Quinn, Gerald J Atkins, Chi Ly, Christine Gange, Vicky Kartsogiannis, Jan Elliott, Panagiota Kostakis, Andrew Cw Zannettino, Brett Cromer, William J Mckinstry, David M Findlay, Matthew T Gillespie, Kong Wah Ng|
|Abstract:||Osteoclast inhibitory lectin (OCIL) is a newly recognized inhibitor of osteoclast formation. We identified a human homolog of OCIL and its gene, determined its regulation in human osteoblast cell lines, and established that it can inhibit murine and human osteoclast formation and resorption. OCIL shows promise as a new antiresorptive.|
|Keywords:||osteoclasts; C-type lectin; natural killer cell receptors; natural killer gene complex; bone resorption|
|Description:||Copyright © by the American Society for Bone and Mineral Research. Published versions of the genetic sequence discussed by the authors are available via the description links below.|
|Appears in Collections:||Medicine publications|
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