Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/95924
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Type: Journal article
Title: A case of REM sleep behavior disorder, narcolepsy-cataplexy, parkinsonism, and rheumatoid arthritis
Author: Cosentino, F.
Distefano, A.
Plazzi, G.
Schenck, C.
Ferri, R.
Citation: Behavioural Neurology, 2014; 2014:572931-1-572931-6
Publisher: Hindawi
Issue Date: 2014
ISSN: 0953-4180
1875-8584
Statement of
Responsibility: 
Filomena I. I. Cosentino, Angela Distefano, Giuseppe Plazzi, Carlos H. Schenck and Raffaele Ferri
Abstract: A patient is reported in whom signs and symptoms of REM sleep behavior disorder (RBD) and narcolepsy have been associated for almost two decades with a late development of parkinsonism and rheumatoid arthritis. A 78-year-old male patient in whom RBD was first diagnosed was followed-up by clinical examination, video-polysomnography, multiple sleep latency test, cerebral magnetic resonance imaging, and dopamine transporter imaging by single-photon emission computerized tomography. The patient was found to present for almost two decades, in addition to RBD, also narcolepsy. Moreover, a late development of parkinsonism and the occurrence of rheumatoid arthritis were detected and clinically and instrumentally characterized. Patients predisposed to RBD and later parkinsonism might be susceptible to a variety of triggers that, in our patient, might have been represented by a possible latent autoimmune process leading to the development of narcolepsy with cataplexy and rheumatoid arthritis, later.
Keywords: Arthritis, Rheumatoid; Parkinsonian Disorders; Narcolepsy; REM Sleep Behavior Disorder; Magnetic Resonance Imaging; Polysomnography
Rights: © 2014 Filomena I. I. Cosentino et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
RMID: 0030037400
DOI: 10.1155/2014/572931
Appears in Collections:Medicine publications

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