Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/96397
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Type: Journal article
Title: Comorbidities of sleep disorders in childhoodand adolescence: focus on migraine
Author: Dosi, C.
Riccioni, A.
della Corte, M.
Novelli, L.
Ferri, R.
Bruni, O.
Citation: Nature and Science of Sleep, 2013; 5:77-85
Publisher: Dove Medical Press
Issue Date: 2013
ISSN: 1179-1608
1179-1608
Statement of
Responsibility: 
Claudia Dosi, Assia Riccioni, Martina della Corte, Luana Novelli, Raffaele Ferri, Oliviero Bruni
Abstract: The correlation and/or comorbidity between sleep disorders and headache has been reported in numerous studies, but the exact nature of the association between headache, disordered sleep, and underlying mechanisms remains poorly understood. The bidirectional association between sleep and headache is mediated by a temporal link (headache occurs during sleep, after sleep, and in relationship with sleep stages), by a quantitative relationship (excess, lack, bad quality, short duration of sleep may trigger headache), and by a reciprocal connection (headache may cause sleep disruption and may be associated with several sleep disturbances). This association is most evident for primary headache disorders, especially in childhood. A congenital alteration of neurotransmitter pathways (serotoninergic and dopaminergic) might predispose individuals to both disorders, presenting as sleep–wake rhythm disorder in infancy or as headache disorder later in childhood, as result of this neurotransmitter imbalance. Clinicians should be aware that a complete clinical evaluation of childhood headache includes a careful sleep history, taking into account that the treatment of sleep disturbances could lead to an improvement of headache symptoms and vice versa.
Keywords: sleep; headache; migraine; childhood; adolescence
Rights: © 2013 Dosi et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
RMID: 0030037407
DOI: 10.2147/NSS.S34840
Appears in Collections:Medicine publications

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