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https://hdl.handle.net/2440/96581
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dc.contributor.author | McKercher, C. | - |
dc.contributor.author | Chan, H. | - |
dc.contributor.author | Clayton, P. | - |
dc.contributor.author | McDonald, S. | - |
dc.contributor.author | Jose, M. | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | Nephrology, 2014; 19(10):610-616 | - |
dc.identifier.issn | 1320-5358 | - |
dc.identifier.issn | 1320-5358 | - |
dc.identifier.uri | http://hdl.handle.net/2440/96581 | - |
dc.description.abstract | Aim: Whilst increasing numbers of elderly people in Australia are commencing dialysis, few Indigenous patients are aged ≥65 years and their outcomes are unknown. We compared the long-term survival, mortality hazards and causes of death between elderly Indigenous and elderly non-Indigenous dialysis patients. Methods: This was a retrospective cohort study of adults aged ≥65 years who commenced dialysis in Australia from 2001–2011, identified from the Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry. Indigenous (n= 263) and non-Indigenous (n= 10713) patients were followed until death, loss to follow-up, recovery of renal function or 31 December 2011. Mortality was compared using a multivariate Cox proportional-hazards model with age, gender, body mass index, smoking, primary renal disease, comorbidities, late referral and initial treatment modality as predictive variables. Results: Median follow-up was 26.9 months (interquartile range 11.3–48.8 months). Overall 166 Indigenous and 6265 non-Indigenous patients died during the 11-year follow-up period. Mortality rates per 100 patient-years were 23.9 for Indigenous patients and 21.2 for non-Indigenous patients. The overall 1-, 3- and 5-year survival rates were 81%, 49% and 27% for Indigenous patients and 82%, 55% and 35% for non-Indigenous patients respectively. Indigenous patients had a 20% increased risk of mortality compared with non-Indigenous patients (adjusted hazard ratio 1.20, 95% confidence interval, 1.02, 1.41;P= 0.02). ‘Social deaths’ (predominantly dialysis withdrawal) and cardiac deaths were the main causes of death for both groups. Conclusion: Among elderly dialysis patients in Australia, Indigenous status remains an important factor in predicting survival. | - |
dc.description.statementofresponsibility | Charlotte McKercher, Hoi Wong Chan, Philip A Clayton, Stephen McDonald, and Matthew D Jose | - |
dc.language.iso | en | - |
dc.publisher | Blackwell Science | - |
dc.rights | © 2014 Asian Pacific Society of Nephrology | - |
dc.source.uri | http://dx.doi.org/10.1111/nep.12317 | - |
dc.subject | dialysis; end-stage kidney disease; epidemiology; high risk populations | - |
dc.title | Dialysis outcomes of elderly Indigenous and non-Indigenous Australians | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1111/nep.12317 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Clayton, P. [0000-0001-9190-6753] | - |
dc.identifier.orcid | McDonald, S. [0000-0001-6103-1386] | - |
Appears in Collections: | Aurora harvest 3 Medicine publications |
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