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Type: Journal article
Title: Interaction between host cells and microbes in chemotherapy-induced mucositis
Author: Stringer, A.
Citation: Nutrients, 2013; 5(5):1488-1499
Publisher: MDPI
Issue Date: 2013
ISSN: 2072-6643
Statement of
Andrea M. Stringer
Abstract: Cancer patients receiving chemotherapy often develop mucositis as a direct result of their treatment. Recently, the intestinal microbiota has attracted significant attention in the investigation of the pathobiology of mucositis, with a number of studies investigating the effects of chemotherapeutic agents on the microbiota. With significant effects on the intestinal microbiota occurring following the administration of chemotherapy, there is now interest surrounding the downstream pathological effects that may be associated with the altered intestinal ecology. This review seeks to identify links between signalling pathways previously demonstrated to have a role in the development of mucositis, and the altered intestinal microbiota.
Keywords: intestine; microbiota; chemotherapy; mucositis; toll like receptors; mitogen activated protein kinase
Description: This article belongs to the Special Issue: Gut Microbiota and Gut Function
Rights: © 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (
DOI: 10.3390/nu5051488
Appears in Collections:Aurora harvest 7
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