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Type: Journal article
Title: The coronary slow flow phenomenon - A new coronary microvascular disorder
Author: Beltrame, J.
Limaye, S.
Horowitz, J.
Citation: Cardiology: international journal of cardiovascular medicine, surgery and pathology, 2002; 97(4):197-202
Publisher: Karger
Issue Date: 2002
ISSN: 0008-6312
Statement of
Beltrame, John F., Limaye, Sananand B. and Horowitz, John D.
Abstract: The coronary slow flow phenomenon is an angiographic finding characterized by delayed distal vessel opacification in the absence of significant epicardial coronary disease. Case-control and observational studies of patients with this phenomenon were conducted to determine the associated clinical features and prognosis. Patients with coronary slow flow (n = 47) differed from controls (n = 47), more often being current smokers (32 vs. 9%; p < 0.01) and presenting with rest pain requiring urgent admission (74 vs. 21%; p < 0.001), usually to the coronary care unit (66 vs. 17%; p < 0.01). During a median 21-month follow-up of 64 slow flow patients, 84% had recurrent chest pain. Based upon these findings and those of previous investigators, it is speculated that coronary slow flow is a new disease entity characterized by acute but recurrent perturbations of microvascular function.
Keywords: Angiography
Syndrome X
Unstable angina
Description: Copyright © 2002 S. Karger AG, Basel
DOI: 10.1159/000063121
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