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Type: Journal article
Title: Identification of conserved and diverse metabolic shifts during rice grain development
Author: Hu, C.
Tohge, T.
Chan, S.A.
Song, Y.
Rao, J.
Cui, B.
Lin, H.
Wang, L.
Fernie, A.R.
Zhang, D.
Shi, J.
Citation: Scientific Reports, 2016; 6(1):20942-1-20942-12
Publisher: Nature Publishing Group
Issue Date: 2016
ISSN: 2045-2322
Statement of
Chaoyang Hu, Takayuki Tohge, Shen-An Chan, Yue Song, Jun Rao, Bo Cui, Hong Lin, Lei Wang, Alisdair R. Fernie, Dabing Zhang & Jianxin Shi
Abstract: Seed development dedicates to reserve synthesis and accumulation and uncovering its genetic and biochemical mechanisms has been a major research focus. Although proteomic and transcriptomic analyses revealed dynamic changes of genes and enzymes involved, the information regarding concomitant metabolic changes is missing. Here we investigated the dynamic metabolic changes along the rice grain development of two japonica and two indica cultivars using non-targeted metabolomics approach, in which we successfully identified 214 metabolites. Statistical analyses revealed both cultivar and developmental stage dependent metabolic changes in rice grains. Generally, the stage specific metabolic kinetics corresponded well to the physiological status of the developing grains, and metabolic changes in developing rice grain are similar to those of dicot Arabidopsis and tomato at reserve accumulation stage but are different from those of dicots at seed desiccation stage. The remarkable difference in metabolite abundances between japonica and indica rice grain was observed at the reserve accumulation stage. Metabolite-metabolite correlation analysis uncovered potential new pathways for several metabolites. Taken together, this study uncovered both conserved and diverse development associated metabolic kinetics of rice grains, which facilitates further study to explore fundamental questions regarding the evolution of seed metabolic capabilities as well as their potential applications in crop improvement.
Keywords: Seeds
Chromatography, High Pressure Liquid
Cluster Analysis
Gas Chromatography-Mass Spectrometry
Metabolic Networks and Pathways
Biological Evolution
Edible Grain
Rights: This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit
DOI: 10.1038/srep20942
Appears in Collections:Agriculture, Food and Wine publications
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